何 隽 （副教授/博士）
出生年月 ：1982.07
民族：汉
学科专业：药物化学
研究方向：天然药物化学
电子邮箱：2015048@mail.scuec.edu.cn
教育和工作简历：
1. 2021/1-至今，金沙威尼斯欢乐娱人城，药学院，副教授，硕士生导师
2. 2015/7-2021/1，金沙威尼斯欢乐娱人城，药学院，讲师，硕士生导师
3. 2010/7-2015/6，中国科学院昆明植物研究所，植物化学与西部植物资源持续利用国家重点实验室，助理研究员
4. 2005/9–2010/6，中国科学院昆明植物研究所，硕/博，药物化学，博士
5. 2000/9–2004/7，西南大学，学士
研究方向：
传统药用植物及其内生菌化学成分与功能
学术研究
从事传统药用植物和植物内生菌功能性分子的发现，目前已经发现新的天然产物400余个，多个分子被评为研究热点。主持国家自然科学基金、省部级项目等科研基金8项，在Org Lett，J Nat Prod等多种学术期刊以第一作者或通讯作者发表研究论文30余篇；获授权专利2项。
（1）主要科研基金:
1. 国家自然科学基金面上项目，22177139、猕猴桃内生菌抑制其溃疡病病原菌Psa的物质基础及作用机制、63万元、主持。
2. 国家自然科学基金青年科学基金项目，81102347、荚蒾属植物萜类成分及其生物活性研究、20万元、主持。
3. 湖北省自然科学基金项目，棕灰口蘑中“口蘑三萜”分子的发掘及其抗炎作用研究、3万元、主持。
4. 校中央专项，CZY16010、藕带的化学成分及生物活性研究、4万元、主持。
5. 校中央专项，CZT18011、白坚木类生物碱的发掘研究、7万元、主持。
6. NSFC-云南省联合基金项目，U0932602、西南地区特有蕨类植物中先导化合物发现与作用机制研究、180万元、核心成员。
（2）部分论著：
1. Jun-Jie Yu, Ying-Xue Jin, Shan-Shan Huang, Juan He*. Sesquiterpenoids and xanthones from the kiwifruit-associated fungus Bipolaris sp. and their anti-pathogenic microorganism activity. Journal of Fungi 2022, 8, 9.
2. Quan Dai, Fa-Lei Zhang, Zheng-Hui Li, Juan He*, Tao Feng*. Immunosuppressive sesquiterpenoids from the edible mushroom Craterellus odoratus. Journal of Fungi 2021, 7, 1052.
3. Juan He, Rui Ma, Zheng-Hui Li, Tao Feng*, and Ji-Kai Liu*. Taccachatrones A−G, highly oxidized steroids from the rhizomes of Tacca chantrierii and their cytotoxicity assessment. Journal of Natural Products 2021, 84, 2265−2271.
4. Jin-Tao Ma, Jiao-Xian Du, Yan Zhang, Ji-Kai Liu, Tao Feng, Juan He*. Natural imidazole alkaloids as antibacterial agents against Pseudomonas syringae pv. actinidiae isolated from kiwi endophytic fungus Fusarium tricinctum. Fitoterapia 2022, 156, 105070.
5. Juan He, Chao-Jun Pu, Meng Wang, Zheng-Hui Li, Tao Feng,* Da-Ke Zhao,* Ji-Kai Liu,* Conosiligins A−D, ring-rearranged tremulane sesquiterpenoids from Conocybe siliginea. J. Nat. Prod. 2020, 83, 2743−2748.
6. Yu Liang, Wen-Xuan Wang, Xing Wu, Meng Wang, Chao-Jun Pu, Zheng-Hui Li, Tao Feng, Juan He,* Ji-Kai Liu.* Panisuffrutin A, a highly degraded seco-triterpene derivative from Paeonia suffruticosa var. papaveracea (Andr.) Kerner. Tetrahedron Letters 2019, 60, 1838-1840.
7. Juan He, Fa-Lei Zhang, Zheng-Hui Li, Hui-Xiang Yang, Qian Shao, Tao Feng,* Ji-Kai Liu,* Monoterpenoid indole alkaloids from the bark of Melodinus henryi. Fitoterapia 2019, 138, 104354.
8. Juan He, Man-Si Yang, Wen-Xiang Wang, Zheng-Hui Li, Waill Ahmed Mohamed Elkhateeb, Ting-Chi Wen, Hong-Lian Ai*, Tao Feng*. Anti-phytopathogenic sesquiterpenoid-xanthoneadducts from potato endophytic fungus Bipolaris eleusines. RSC Advances 2019, 9, 128–131.
9. Wei Li1, Juan He1, Tao Feng*, Hui-Xiang Yang, Hong-Lian Ai, Zheng-Hui Li, Ji-Kai Liu*. Antroalbocin A, an antibacterial sesquiterpenoid from higher fungus Antrodiella albocinnamomea, Organic Letters 2018, 20, 8019–8021.
10. Tao Feng, Kai-Ting Duan, Shi-Jun He, Bin Wu, Yong-Sheng Zheng, Hong-Lian Ai, Zheng-Hui Li, Juan He, Jian-Ping Zuo, and Ji-Kai Liu, Ophiorrhines A and B, two immunosuppressive monoterpenoid indole alkaloids from Ophiorrhiza japonica. Organic Letters, 2018, 20, 7926–7928.
11. Xuan-Qin Chen, Li-Dong Shao, Mahesh Pal, Yu Shen, Xiao Cheng, Gang Xu, Li-Yan Peng, Kou Wang, Zheng-Hong Pan, Ming-Ming Li, Ying Leng, Juan He*, Qin-Shi Zhao*. Hupehenols A–E, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors from Viburnum hupehense. Journal of Natural Products 2015, 78, 330−334.
12. Jin-Tang Cheng, Fei Liu, Xiao-Nian Li, Xing-De Wu, Liao-Bin Dong, Li-Yan Peng, Sheng-Xiong Huang, Juan He*, Qin-Shi Zhao* Lycospidine A, a new type ofLycopodium alkaloid from Lycopodium complanatum. Organic Letters 2013, 15, 2438-2441.
13. Gao Xiu, Li-Dong Shao, Liao-Bin Dong, Xiao Cheng, Xing-De Wu, Fei Liu, Wei-Wei Jiang, Li-Yan Peng, Juan He,* Qin-Shi Zhao.* Vibsatins A and B, two new tetranorvibsane-type diterpenoids from Viburnum tinus cv. Variegatus. Organic Letters 2014, 16, 980−983.
14. Juan He, Li-Yan Peng, Lin Tu, Xing-De Wu, Liao-Bing Dong, Zheng-Hong Pan, Xuan-Qin Cheng, Jia Su, Yu Zhao, Gang Xu, Xiao Cheng, Yan Li, Qin-Shi Zhao*. Vibsane-type diterpenes from leaves and twigs of Viburnum odoratissium. Fitoterapia 2016, 109: 224-229.
15. Juan He, Xuan-Qin Chen, Ming-Ming Li, Yu Zhao, Gang Xu, Xiao Cheng, Li-Yan Peng, Min-Jin Xie, Yong-Tang Zheng, Yi-Ping Wang, Qin-Shi Zhao* Lycojapodine A, a novel alkaloid from Lycopodium japonicum. Organic Letters 2009, 11, 1397-1400.
（3）授权专利：
何隽，艾洪莲，李正辉，冯涛。蟋蟀草平脐蠕孢菌素I及其制备方法与应用、蟋蟀草平脐蠕孢菌素J及其制备方法与应用，发明专利，CN109503613B。
