出生年月:1988年12月
民 族:汉族
职 称:副教授
学科专业:高分子化学
电子邮箱:2023143@mail.scuec.edu.cn
教育经历:
2007.09 – 2011.06,武汉大学化学与分子科学学院,化学基地班,理学学士
2011.09 – 2017.01,中国科学院长春应用化学研究所, 高分子化学与物理,理学博士
工作经历:
2017.05 – 2020.01,美国康奈尔大学,博士后
2020.02 – 2022.05,美国普渡大学,博士后
2022.11 – 2023.09,湖北大学材料科学与工程学院,讲师
2023.10至今,金沙威尼斯欢乐娱人城药学院,副教授
主要研究方向:
1.水凝胶材料的制备及在三维细胞培养、组织修复和药物递送方面的应用研究
2.高分子纳米载体的制备及在药物传输和疾病治疗方面的应用研究
承担的项目:
湖北省自然科学基金青年项目(2023AFB421),2023-2025,主持
发表论文:
1. Mazin H Hakim, Brian H Jun, Adib Ahmadzadegan, Paulina M Babiak, Qinghua Xu, Kevin P Buno, Julie C Liu, Arezoo M Ardekani, Pavlos P Vlachos*, Luis Solorio*. Investigation of macromolecular transport through tunable collagen hyaluronic acid matrices. Colloids and Surfaces B: Biointerfaces, 222 (2023) 113123.
2. Qinghua Xu*, Jessica E. Torres, Mazin Hakim, Paulina M. Babiak, Pallabi Pal, Carly M. Battitoni, Michael Nguyen, Alyssa Panitch, Luis Solorio, Julie Liu*. Collagen- and hyaluronic acid-based hydrogels and their biomedical applications. Materials Science and Engineering R, 146 (2021) 100641.
3. Qinghua Xu, Chih-Chang Chu*. A novel Pseudo-protein-based ROS-responsive nanoparticle for anticancer drug delivery. Journal of Biomedical Materials Research Part A, 2021, 109A: 524-537.
4. Hiu Yee Kwan, Qinghua Xu, Ruihong Gong, Zhaoxiang Bian, Chih-Chang Chu. Targeted Chinese medicine delivery by a new family of biodegradable pseudo-protein nanoparticles for treating triple-negative breast cancer: in vitro and in vivo study. Frontiers in Oncology, 2020 (10), 600298.
5. Zhen Zhang, Chaoliang He, Qinghua Xu, Xiuli Zhuang, Xuesi Chen. Preparation of Poly (L-glutamic acid)-based Hydrogels via Diels-Alder Reaction and Study on Their Biomolecule-responsive Properties. ACTA POLYMERICA SINICA, 2018 (1) 99-108.
6. Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Xuesi Chen*. Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion. Biomacromolecules, 2017, 18 (4), 1411–1418.
7. Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*. Injectable, biomolecule-responsive polypeptide hydrogels with triggered degradation capacity for cell encapsulation and facile cell recovery. ACS Applied Materials & Interfaces, 2016, 8 (45), 30692-30702.
8. Qinghua Xu, Chaoliang He*, Kaixuan Ren, Chunsheng Xiao, Xuesi Chen*. Thermosensitive polypeptide hydrogels as a platform for ROS-triggered cargo release with innate cytoprotective ability under oxidative stress. Advanced Healthcare Materials, 2016, 5 (15); 1979-1990.
9. Qinghua Xu, Chaoliang He*, Chunsheng Xiao, and Xuesi Chen*. Reactive oxygen species (ROS) responsive polymers for biomedical applications. Macromolecular Bioscience, 2016; 16 (5); 635-646.
10. Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Shuangjiang Yu and Xuesi Chen*. ε-Methacryloyl-L-lysine based polypeptides and their thiol-ene click functionalization. Polymer Chemistry, 2015; 6; 1758-1767.